Rejuvenate Your Skin with Polynucleotide Treatment in London

What Is Polynucleotide Treatment?

Polynucleotide treatment is a scientifically advanced injectable skin treatment that targets the skin’s regeneration systems to enhance skin quality, firmness, and glow. This next-generation innovation uses highly purified DNA fragments known as polynucleotides—naturally derived molecules that stimulate your body’s regenerative processes to improve skin elasticity, smoothness, and resilience.
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Unlike a dermal filler, polynucleotides do not artificially add volume. Instead, they stimulate your skin to produce its own collagen, boosting long-term skin hydration and repair. At our London clinic, we specialise in personalised treatment plans that deliver safe, natural-looking results with minimal downtime.

What Can Polynucleotide Treatment Help With?

This versatile injectable is used for a wide range of treatments, offering an excellent alternative or complement to traditional anti-wrinkle therapies and dermal fillers. Our patients choose polynucleotides to:

This cosmetic solution is especially popular for patients seeking aesthetic rejuvenation around the eye, where traditional filler options may not be suitable.

How Do Polynucleotides Work?

Polynucleotide injections go beyond surface-level beauty. These treatments act on the cellular level, where real skin rejuvenation occurs. When we inject polynucleotides into the dermis, the process begins:

Cellular Stimulation

The DNA fragments encourage fibroblasts to produce new elastin and collagen.

Deep Hydration

Polynucleotides bind to water molecules, promoting long-lasting skin hydration.

Tissue Regeneration

Healing and cell turnover are accelerated, leading to visibly improved skin texture and tone.

Anti-Inflammatory Action

Reduces redness and supports healing of irritated or post-inflammatory skin.

Whether targeting the area around the eye or full face, polynucleotide treatment is a regenerative option unlike any other aesthetic injectable.

What to Expect During Your Skin Treatment

Every treatment session at the Institute of Medical Physics begins with a personalised consultation to fully understand your skin’s condition, history, and long-term goals. We believe in precision from the start, ensuring your injectable treatment is as effective and comfortable as possible.

Initial Consultation

Your journey begins with a one-on-one session with one of our expert clinicians. During this time, we’ll review your medical history, assess your current skin quality, and determine if you’re an ideal candidate for polynucleotide treatment.

First Cosmetic Treatment

On the day of your first treatment, your skin will be gently cleansed and prepped using medical-grade antiseptics. A topical numbing cream is then applied to minimise any discomfort from the injections. The procedure itself is quick, targeted, and carefully mapped out according to the plan discussed in your consultation.

Injection Site Care

After your injectable treatment, you may experience minor redness, a small bruise, or slight swelling at the injection site. These effects are entirely normal and typically resolve within 24–48 hours. Most patients return to their normal activities the same day. We recommend avoiding intense physical activity, alcohol, and heat-based skincare for the first 24 hours to ensure smooth healing.

Aftercare

We’ll provide you with comprehensive aftercare instructions to maximise your results and minimise downtime. This includes guidelines for gentle cleansing, sun protection, and recommended skincare products to support your skin’s rejuvenation. Following these steps ensures your body can fully absorb the polynucleotides and begin its natural repair process.

Maintenance Session

To achieve and maintain optimal results, we typically advise an initial course of three treatment sessions spaced two to three weeks apart. This allows the polynucleotides to stimulate ongoing elastin and collagen production and progressively improve skin tone and texture.

Why Patients Choose Our London Clinic

At the Institute of Medical Physics, our combination of scientific expertise, personalised care, and groundbreaking technology has earned us a reputation as one of London’s most trusted names in advanced treatments. We take pride in offering a truly tailored experience that prioritises safety, results, and patient satisfaction at every stage of your skin treatment journey.

Clinical Precision

Each injectable treatment is delivered by medically qualified professionals with deep expertise in skin rejuvenation. We use evidence-based protocols and clinically validated techniques to ensure precision, consistency, and optimal outcomes.

Customised Treatment Plans

No two faces—or skin concerns—are alike. That’s why we design an individualised treatment plan based on a detailed skin assessment.

Innovation with Integrity

Our clinic is led by Dr. Emanuel Paleco, a renowned innovator in medical laser and aesthetic sciences. With over three decades of pioneering research in biochemical pathways, Dr. Paleco has introduced numerous technologies that are now considered gold standards in aesthetic care.

Trusted Cosmetic Care

We are more than just an aesthetic clinic—we are a centre for excellence in skin health. Our patients trust us not only because of the results we achieve but also because of the environment we cultivate.

Real, Lasting Results

Unlike quick-fix solutions, our approach is grounded in supporting the skin’s natural healing mechanisms. By stimulating elastin and collagen production at the cellular level, we help your skin restore its own structure and vitality.

Polynucleotide Treatment Pricing

At the Institute of Medical Physics, we are committed to clear, transparent pricing that reflects the quality, expertise, and scientific precision of our treatments. We understand that investing in your skincare and overall skin health is a personal decision, which is why we provide a full breakdown of costs upfront—no hidden fees, no surprise add-ons.

Price Overview:

Additional areas or combination plans can be discussed during your consultation.

About the Institute of Medical Physics

The Institute of Medical Physics, founded by leading laser scientist Dr. Emanuel Paleco and Dr. Saif Chatoo, is a centre of excellence for science-backed aesthetic treatments in London. With a flagship clinic in King’s Cross and affiliated pharmacies in North London and Essex, we offer advanced injectable and aesthetic solutions rooted in decades of medical research and innovation.
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Dr. Paleco’s expertise in quantum nuclear engineering and biochemical regeneration has shaped our approach to modern skin treatment—combining cutting-edge science with clinical precision. From polynucleotide injections to laser therapies, our treatments are designed to improve not just appearance, but overall skin health at the cellular level.
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At our clinic, we prioritise personalised care, long-term results, and non-invasive procedures that stimulate collagen and elastin, enhance hydration, and support natural rejuvenation. Whether you’re seeking under-eye rejuvenation or full facial revitalisation, we deliver outcomes that are safe, effective, and grounded in evidence—not trends.

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Frequently Asked Questions