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The Ultimate Guide to Polynucleotide Injections (2025)

The Ultimate Guide to Polynucleotide Injections (2025)

Content of this Paper

As more people look for effective, science-backed anti-aging treatments, polynucleotides are emerging as a go-to option for improving skin quality, hydration, and overall resilience. Here, you’ll find practical insights into what to expect from the treatment in 2025, including its potential benefits and key considerations, whether you’re exploring it for the first time or keeping up with the latest in skincare innovation

Key Takeaways

  • Polynucleotide injections are an increasingly popular method for skin rejuvenation.
  • Polynucleotide injections help in skin repair and combat signs of ageing.
  • Understanding the procedure will prepare you for your treatment experience.
  • Knowledge of potential side effects is crucial for safety.

What Are Polynucleotide Injections?

Polynucleotide injections are cosmetic treatments that use biopolymers to support skin regeneration and rejuvenation. These injections contain sequences of nucleotides, essential building blocks involved in key biological processes. By harnessing this science, polynucleotides help stimulate the body’s natural healing mechanisms, promoting healthier, more youthful skin.

Definition and Science Behind Polynucleotides

The definition of polynucleotides refers to long chains of nucleotides that play vital roles in cellular processes, including the synthesis and repair of DNA and RNA. This foundational knowledge provides insights into the science behind polynucleotides and their applicability in dermatology. 

They stimulate collagen production, a crucial protein for maintaining skin elasticity and firmness. Moreover, their ability to promote tissue regeneration aids in the recovery of damaged skin, showcasing the potential benefits for long-term skin health.

How Polynucleotide Injections Work in Skin Rejuvenation

Understanding how polynucleotide injections work in skin rejuvenation involves examining various skin rejuvenation mechanisms. These injections improve skin texture and tone by boosting collagen production and assisting in the body’s natural healing processes. 

As the ingredients of polynucleotide injections are absorbed, they combat free radicals and enhance overall skin vitality, leading to a refreshed and youthful appearance. 

Benefits of Polynucleotide Injections

Polynucleotide injections offer significant advantages that contribute to your skin’s overall health and appearance. Notably, they enhance hydration levels and improve skin elasticity, leading to a more vibrant and youthful complexion.

Skin Repair and Anti-Aging Effects

The benefits of polynucleotide injections are particularly evident in their ability to stimulate collagen production. This natural response helps to restore and rejuvenate your skin, addressing common signs of aging such as fine lines and wrinkles. 

By enhancing skin repair processes, these injections effectively minimise the appearance of acne scarring and uneven skin tone, creating a smoother and more youthful look.

Hydration and Elasticity Improvements

Another noteworthy aspect of polynucleotide injections is their effectiveness in improving skin hydration and elasticity. Through enhanced moisture retention, your skin appears plumper and healthier. 

This boost in hydration levels not only provides immediate visual improvements but also contributes long-term benefits to your skin elasticity, allowing it to regain its youthful resilience. 

​​Anti-Inflammatory and Soothing Properties

Polynucleotides also possess anti-inflammatory effects that help soothe irritated or sensitive skin. By calming redness and reducing inflammation, these injections can improve skin comfort and accelerate healing after other aesthetic procedures or skin trauma.

Polynucleotide Injections vs. Other Injectable Treatments

With 892,000 aesthetic procedures carried out in the UK in 2024 alone, it’s clear that demand for non-surgical treatments is continuing to rise. As more people explore advanced skincare options, understanding the differences between polynucleotide injections, hyaluronic acid, and growth factors becomes increasingly important. 

Each injectable serves a distinct purpose and offers specific benefits, all of which can play a key role in shaping the right approach to your skin health.

This section highlights the main differences and advantages you may find with polynucleotide injections in comparison to hyaluronic acid and growth factors.

Comparison with Hyaluronic Acid and Growth Factors

Hyaluronic acid primarily functions as a filler, providing immediate volume and hydration to the skin. Conversely, polynucleotide injections stimulate natural regenerative processes within the body, promoting tissue repair and encouraging collagen production. 

While hyaluronic acid delivers short-term enhancements, polynucleotides focus on long-term skin health by strengthening the deeper layers of the skin. For those looking for more lasting rejuvenation, this makes them a compelling alternative.

Polynucleotides

  • Primary function: Stimulate regeneration and collagen production.
  • Mechanism of action: Activate fibroblasts and tissue repair processes.
  • Onset of results: Gradual improvement developing over several weeks.
  • Duration of effect: Long-term improvements with repeated treatments.
  • Depth of action: Targets deeper dermal layers for structural support.
  • Best for: Long-term skin rejuvenation and texture improvement.

Hyaluronic Acid (HA)

  • Primary function: Provide immediate volume and hydration.
  • Mechanism of action: Bind water molecules to hydrate and plump the skin.
  • Onset of results: Immediate to within a few days.
  • Duration of effect: Temporary results, typically lasting 3–6 months.
  • Depth of action: Works mainly on the surface and superficial dermis.
  • Best for: Quick hydration and added volume.

Unique Advantages of Polynucleotides

The advantages of polynucleotides include: 

  • Ability to boost skin elasticity and hydration while facilitating natural healing. 
  • Improve skin elasticity and hydration by supporting cellular health.
  • Promote natural healing and tissue regeneration.
  • Deliver gradual, natural-looking results rather than dramatic, instant changes.
  • Offer a subtle alternative to traditional dermal fillers such as botox.
  • Can be combined with other treatments for a more comprehensive, personalised approach.

What to Expect During a Polynucleotide Injection Treatment

Understanding the polynucleotide treatment process can help ease any anxiety you may have about the injection procedure. This section will outline the essential aspects of the treatment, including the areas treated and some tips for aftercare.

Treatment Procedure Step-by-Step

Before beginning the treatment, you will usually undergo a consultation where your desired results are discussed. Once agreed upon, the procedure may follow these steps:

  1. Preparation: The treatment area is cleaned and sterilised to minimise the risk of infection.
  2. Numbing: A topical anaesthetic is applied to reduce discomfort and pain during the polynucleotide injection procedure.
  3. Injection: Using a fine needle, polynucleotides are precisely injected into the targeted areas treated, such as the full face, under-eye regions, or jawline. The healthcare professional will work methodically to ensure even distribution.
  4. Post-Treatment: After the injections, the area may be massaged gently to enhance absorption and evenly distribute the treatment.
  5. Aftercare Instructions: You will receive guidance on how to care for the treated areas to maximise the effects of skin rejuvenation.

Typical Areas Treated

Polynucleotide injections are versatile and can be used in various locations for effective skin rejuvenation. Common areas treated include:

  • Full face
  • Under-eye regions
  • Jawline
  • Neck
  • Hands

Each of these areas benefits from the polynucleotide treatment process, contributing to improving skin texture, hydration, and overall appearance. Knowing these details can prepare you for your journey towards enhanced skin health.

Potential Side Effects and Safety Considerations

Understanding the potential side effects and safety considerations of polynucleotide injections is crucial for making informed decisions about your treatment. Various reactions can occur, ranging from common to rare. Being aware of these can help you approach your procedure with confidence.

Common and Rare Side Effects

After receiving polynucleotide injections, you might experience some normal reactions. Common polynucleotide injection side effects include:

  • Redness and swelling at the injection site
  • Minor bruising
  • Itching or tenderness

These symptoms typically vanish within a few days. Rare side effects may emerge, though they are not common. These can involve:

  • Severe allergic reactions
  • Infection at the injection site

While such occurrences can be alarming, they represent a small fraction of patients receiving treatment. Maintaining an open dialogue with your healthcare provider before and after the procedure can help manage any concerns and ensure proper care.

Who are Polynucleotide Injections Best For?

Polynucleotide injections are best for for various individuals seeking skin rejuvenation. Understanding who can and can’t have polynucleotide injections is vital for ensuring optimal results. 

Generally, these injections benefit older patients with moderate tissue laxity, as the skin’s natural regenerative abilities decline with age. Polynucleotides play a crucial role in stimulating DNA synthesis and cellular repair, making them a valuable option for revitalising ageing skin.

Who Should Avoid Polynucleotide Injections?

While many may benefit from this treatment, there are some things to consider. Common groups to avoid these injections include:

  • Individuals with active skin infections or inflammation in the treatment area.
  • Those with a history of severe allergies or hypersensitivity to any components of the injection.
  • Patients with autoimmune disorders that may affect healing processes.
  • Pregnant or breastfeeding women, as the effects of the treatment during these phases remain uncertain.
  • People currently undergoing anticoagulant therapy, as this could increase the risk of adverse effects.

By being aware of these potential exceptions, both practitioners and patients can ensure that polynucleotide injections are administered safely, maximising efficacy and minimising risks. 

Aftercare Tips to Maximise Polynucleotide Injection Results

Proper polynucleotide aftercare can significantly enhance your treatment outcomes. Regular maintenance treatments also ensure long-lasting benefits, helping you maintain that rejuvenated appearance.

Post-Treatment Skincare and Lifestyle Recommendations

After undergoing polynucleotide injections, your skincare routine should focus on hydration and protection. Here are essential post-treatment skincare tips:

  • Keep the treated area clean and avoid touching it with unwashed hands.
  • Hydrate your skin using a gentle moisturiser, preferably with hyaluronic acid.
  • Incorporate a broad-spectrum sunscreen to prevent UV damage.
  • Stay away from harsh skincare products, such as those with retinoids or acids, for at least a week.

In terms of lifestyle recommendations, consider adopting these practices:

  • Increase your water intake to maintain skin hydration.
  • Avoid smoking and limit alcohol consumption to enhance your skin's recovery.
  • Incorporate a balanced diet rich in vitamins A, C, and E, which are vital for skin health.
  • Engage in light physical activities to promote blood circulation while avoiding strenuous workouts for a few days.

Maintenance and Follow-Up Sessions

Scheduling regular maintenance treatments is essential for sustaining the effects of polynucleotide injections. Follow-up sessions can vary depending on your skin’s response and desired outcomes. 

Generally speaking, consider the following:

  1. Initial follow-up: 4 to 6 weeks post-treatment to assess results.
  2. Regular touch-ups: Every 3 to 6 months to maintain skin quality.

Discuss any concerns with your practitioner to modify your treatment plan as necessary.

Adhering to a dedicated polynucleotide aftercare plan contributes significantly to your skin's rejuvenation. Engaging in thoughtful post-treatment skincare, along with lifestyle changes and planned maintenance sessions, will ensure that you enjoy the long-term benefits of your polynucleotide injections.

How Much Do Polynucleotide Injections Cost?

The cost of polynucleotide injections can vary, but here's a general breakdown to help you plan:

  • Per session: Typically ranges from £200 to £600, depending on the clinic, practitioner expertise, and product used.
  • Treatment course: Most patients require 3 to 5 sessions spaced over several weeks for best results.
  • Packages: Some clinics offer discounts or bundled pricing for multiple sessions, so it’s worth asking about available deals.
  • Additional costs: Budget for aftercare products and follow-up appointments, which may not always be included in the session price.

Being aware of the full cost, including extras, can help you make informed decisions and avoid surprises during your treatment journey.

Latest Advances in Polynucleotide Injection Technology (2025)

As the field of aesthetic medicine continues to evolve, the advances in polynucleotide technology have gained significant attention. 

Recent innovations focus on enhancing the application techniques and formulation of these injections, ensuring improved efficacy and patient satisfaction. With each new development, practitioners are better equipped to provide treatments that result in rejuvenated skin and overall enhanced aesthetics.

Innovations and Future Trends

The future trends in polynucleotide injections indicate a shift towards tailor-made solutions for individual patient needs. Advancements in delivery systems, such as micro-needling combined with polynucleotide therapies, are emerging as popular choices, yielding remarkable results in skin texture and elasticity. 

Continuous research is driving the development of more effective formulations, paving the way for more personalised treatment plans.

Expert Opinions and Clinical Studies

Experts in the field have shared their insights on polynucleotide injections through various clinical studies, underscoring the potential benefits of polynucleotide treatments. These studies highlight not only the efficacy but also the safety profile of these injections, reinforcing their place in contemporary aesthetic practices. 

As new data emerges, it is clear that keeping abreast of these clinical findings will empower you to make informed choices regarding your skincare and treatment options.

Before You Go…

As polynucleotide injections continue to reshape the landscape of aesthetic treatments, staying informed is key to making confident, well-rounded decisions about your skincare. If you’re curious to dive deeper into this growing field, whether it's comparing injectable options, learning about the latest technologies, or finding expert advice, explore our related articles for more insights. Your journey to healthier, more radiant skin starts with knowledge.

Read More

  • Do polynucleotides make you look younger?
  • How quickly do polynucleotides work?
  • Can polynucleotides help acne?
  • Can I sleep after polynucleotides?

About Institute of Medical Physics

The Institute of Medical Physics, founded by Dr. Emanuel Paleco, is a premier medical laboratory specialising in Medical and Aesthetic Laser Science.

With a flagship clinic in King’s Cross and additional locations in North London and Essex, the Institute is at the forefront of laser science innovation. Experience advanced laser science and innovative medical treatments.

Book a consultation with Dr. Emanuel Paleco and his expert team at the Institute of Medical Physics.

FAQs

What are the primary benefits of polynucleotide injections?

The primary benefits include skin repair capabilities, anti-aging effects, and improvements in hydration and elasticity. These injections stimulate collagen production, enhance skin texture, and can help reduce fine lines and address issues like acne scarring.

How do polynucleotide injections differ from hyaluronic acid treatments?

While hyaluronic acid mainly adds volume to the skin, polynucleotide injections stimulate the body's natural regenerative processes, offering unique benefits such as promoting tissue repair and fighting free radicals, which can lead to a more youthful appearance.

What can I expect during the polynucleotide injection procedure?

During the procedure, a qualified practitioner will clean the treatment area and administer the injections using a fine needle. You can expect minimal discomfort, and the process usually takes around 30 minutes, depending on the areas treated, which may include the full face, under-eye regions, and jawline.

Are there any side effects associated with polynucleotide injections?

Yes, common side effects include redness, swelling, and tenderness at the injection sites, often considered an inflammatory response. Rare side effects may occur, and it is essential to discuss these with your practitioner before treatment.

Who should consider getting polynucleotide injections?

Ideal candidates are typically older adults experiencing moderate tissue laxity and seeking skin rejuvenation. However, individuals with specific health concerns or conditions should avoid these treatments, which a practitioner will discuss with you during the consultation.

Date First Published:
August 16, 2025
Our Research is Led by Dr. Emanuel Paleco World Renowned Biophysicist
Dr Emmanuel
1000+
Medical Doctors Trained
406+
Trademarks in his field
30+
Years of research
10+
Prestigious Research Awards

The Ultimate Guide to Polynucleotide Injections (2025)

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As more people look for effective, science-backed anti-aging treatments, polynucleotides are emerging as a go-to option for improving skin quality, hydration, and overall resilience. Here, you’ll find practical insights into what to expect from the treatment in 2025, including its potential benefits and key considerations, whether you’re exploring it for the first time or keeping up with the latest in skincare innovation

Key Takeaways

  • Polynucleotide injections are an increasingly popular method for skin rejuvenation.
  • Polynucleotide injections help in skin repair and combat signs of ageing.
  • Understanding the procedure will prepare you for your treatment experience.
  • Knowledge of potential side effects is crucial for safety.

What Are Polynucleotide Injections?

Polynucleotide injections are cosmetic treatments that use biopolymers to support skin regeneration and rejuvenation. These injections contain sequences of nucleotides, essential building blocks involved in key biological processes. By harnessing this science, polynucleotides help stimulate the body’s natural healing mechanisms, promoting healthier, more youthful skin.

Definition and Science Behind Polynucleotides

The definition of polynucleotides refers to long chains of nucleotides that play vital roles in cellular processes, including the synthesis and repair of DNA and RNA. This foundational knowledge provides insights into the science behind polynucleotides and their applicability in dermatology. 

They stimulate collagen production, a crucial protein for maintaining skin elasticity and firmness. Moreover, their ability to promote tissue regeneration aids in the recovery of damaged skin, showcasing the potential benefits for long-term skin health.

How Polynucleotide Injections Work in Skin Rejuvenation

Understanding how polynucleotide injections work in skin rejuvenation involves examining various skin rejuvenation mechanisms. These injections improve skin texture and tone by boosting collagen production and assisting in the body’s natural healing processes. 

As the ingredients of polynucleotide injections are absorbed, they combat free radicals and enhance overall skin vitality, leading to a refreshed and youthful appearance. 

Benefits of Polynucleotide Injections

Polynucleotide injections offer significant advantages that contribute to your skin’s overall health and appearance. Notably, they enhance hydration levels and improve skin elasticity, leading to a more vibrant and youthful complexion.

Skin Repair and Anti-Aging Effects

The benefits of polynucleotide injections are particularly evident in their ability to stimulate collagen production. This natural response helps to restore and rejuvenate your skin, addressing common signs of aging such as fine lines and wrinkles. 

By enhancing skin repair processes, these injections effectively minimise the appearance of acne scarring and uneven skin tone, creating a smoother and more youthful look.

Hydration and Elasticity Improvements

Another noteworthy aspect of polynucleotide injections is their effectiveness in improving skin hydration and elasticity. Through enhanced moisture retention, your skin appears plumper and healthier. 

This boost in hydration levels not only provides immediate visual improvements but also contributes long-term benefits to your skin elasticity, allowing it to regain its youthful resilience. 

​​Anti-Inflammatory and Soothing Properties

Polynucleotides also possess anti-inflammatory effects that help soothe irritated or sensitive skin. By calming redness and reducing inflammation, these injections can improve skin comfort and accelerate healing after other aesthetic procedures or skin trauma.

Polynucleotide Injections vs. Other Injectable Treatments

With 892,000 aesthetic procedures carried out in the UK in 2024 alone, it’s clear that demand for non-surgical treatments is continuing to rise. As more people explore advanced skincare options, understanding the differences between polynucleotide injections, hyaluronic acid, and growth factors becomes increasingly important. 

Each injectable serves a distinct purpose and offers specific benefits, all of which can play a key role in shaping the right approach to your skin health.

This section highlights the main differences and advantages you may find with polynucleotide injections in comparison to hyaluronic acid and growth factors.

Comparison with Hyaluronic Acid and Growth Factors

Hyaluronic acid primarily functions as a filler, providing immediate volume and hydration to the skin. Conversely, polynucleotide injections stimulate natural regenerative processes within the body, promoting tissue repair and encouraging collagen production. 

While hyaluronic acid delivers short-term enhancements, polynucleotides focus on long-term skin health by strengthening the deeper layers of the skin. For those looking for more lasting rejuvenation, this makes them a compelling alternative.

Polynucleotides

  • Primary function: Stimulate regeneration and collagen production.
  • Mechanism of action: Activate fibroblasts and tissue repair processes.
  • Onset of results: Gradual improvement developing over several weeks.
  • Duration of effect: Long-term improvements with repeated treatments.
  • Depth of action: Targets deeper dermal layers for structural support.
  • Best for: Long-term skin rejuvenation and texture improvement.

Hyaluronic Acid (HA)

  • Primary function: Provide immediate volume and hydration.
  • Mechanism of action: Bind water molecules to hydrate and plump the skin.
  • Onset of results: Immediate to within a few days.
  • Duration of effect: Temporary results, typically lasting 3–6 months.
  • Depth of action: Works mainly on the surface and superficial dermis.
  • Best for: Quick hydration and added volume.

Unique Advantages of Polynucleotides

The advantages of polynucleotides include: 

  • Ability to boost skin elasticity and hydration while facilitating natural healing. 
  • Improve skin elasticity and hydration by supporting cellular health.
  • Promote natural healing and tissue regeneration.
  • Deliver gradual, natural-looking results rather than dramatic, instant changes.
  • Offer a subtle alternative to traditional dermal fillers such as botox.
  • Can be combined with other treatments for a more comprehensive, personalised approach.

What to Expect During a Polynucleotide Injection Treatment

Understanding the polynucleotide treatment process can help ease any anxiety you may have about the injection procedure. This section will outline the essential aspects of the treatment, including the areas treated and some tips for aftercare.

Treatment Procedure Step-by-Step

Before beginning the treatment, you will usually undergo a consultation where your desired results are discussed. Once agreed upon, the procedure may follow these steps:

  1. Preparation: The treatment area is cleaned and sterilised to minimise the risk of infection.
  2. Numbing: A topical anaesthetic is applied to reduce discomfort and pain during the polynucleotide injection procedure.
  3. Injection: Using a fine needle, polynucleotides are precisely injected into the targeted areas treated, such as the full face, under-eye regions, or jawline. The healthcare professional will work methodically to ensure even distribution.
  4. Post-Treatment: After the injections, the area may be massaged gently to enhance absorption and evenly distribute the treatment.
  5. Aftercare Instructions: You will receive guidance on how to care for the treated areas to maximise the effects of skin rejuvenation.

Typical Areas Treated

Polynucleotide injections are versatile and can be used in various locations for effective skin rejuvenation. Common areas treated include:

  • Full face
  • Under-eye regions
  • Jawline
  • Neck
  • Hands

Each of these areas benefits from the polynucleotide treatment process, contributing to improving skin texture, hydration, and overall appearance. Knowing these details can prepare you for your journey towards enhanced skin health.

Potential Side Effects and Safety Considerations

Understanding the potential side effects and safety considerations of polynucleotide injections is crucial for making informed decisions about your treatment. Various reactions can occur, ranging from common to rare. Being aware of these can help you approach your procedure with confidence.

Common and Rare Side Effects

After receiving polynucleotide injections, you might experience some normal reactions. Common polynucleotide injection side effects include:

  • Redness and swelling at the injection site
  • Minor bruising
  • Itching or tenderness

These symptoms typically vanish within a few days. Rare side effects may emerge, though they are not common. These can involve:

  • Severe allergic reactions
  • Infection at the injection site

While such occurrences can be alarming, they represent a small fraction of patients receiving treatment. Maintaining an open dialogue with your healthcare provider before and after the procedure can help manage any concerns and ensure proper care.

Who are Polynucleotide Injections Best For?

Polynucleotide injections are best for for various individuals seeking skin rejuvenation. Understanding who can and can’t have polynucleotide injections is vital for ensuring optimal results. 

Generally, these injections benefit older patients with moderate tissue laxity, as the skin’s natural regenerative abilities decline with age. Polynucleotides play a crucial role in stimulating DNA synthesis and cellular repair, making them a valuable option for revitalising ageing skin.

Who Should Avoid Polynucleotide Injections?

While many may benefit from this treatment, there are some things to consider. Common groups to avoid these injections include:

  • Individuals with active skin infections or inflammation in the treatment area.
  • Those with a history of severe allergies or hypersensitivity to any components of the injection.
  • Patients with autoimmune disorders that may affect healing processes.
  • Pregnant or breastfeeding women, as the effects of the treatment during these phases remain uncertain.
  • People currently undergoing anticoagulant therapy, as this could increase the risk of adverse effects.

By being aware of these potential exceptions, both practitioners and patients can ensure that polynucleotide injections are administered safely, maximising efficacy and minimising risks. 

Aftercare Tips to Maximise Polynucleotide Injection Results

Proper polynucleotide aftercare can significantly enhance your treatment outcomes. Regular maintenance treatments also ensure long-lasting benefits, helping you maintain that rejuvenated appearance.

Post-Treatment Skincare and Lifestyle Recommendations

After undergoing polynucleotide injections, your skincare routine should focus on hydration and protection. Here are essential post-treatment skincare tips:

  • Keep the treated area clean and avoid touching it with unwashed hands.
  • Hydrate your skin using a gentle moisturiser, preferably with hyaluronic acid.
  • Incorporate a broad-spectrum sunscreen to prevent UV damage.
  • Stay away from harsh skincare products, such as those with retinoids or acids, for at least a week.

In terms of lifestyle recommendations, consider adopting these practices:

  • Increase your water intake to maintain skin hydration.
  • Avoid smoking and limit alcohol consumption to enhance your skin's recovery.
  • Incorporate a balanced diet rich in vitamins A, C, and E, which are vital for skin health.
  • Engage in light physical activities to promote blood circulation while avoiding strenuous workouts for a few days.

Maintenance and Follow-Up Sessions

Scheduling regular maintenance treatments is essential for sustaining the effects of polynucleotide injections. Follow-up sessions can vary depending on your skin’s response and desired outcomes. 

Generally speaking, consider the following:

  1. Initial follow-up: 4 to 6 weeks post-treatment to assess results.
  2. Regular touch-ups: Every 3 to 6 months to maintain skin quality.

Discuss any concerns with your practitioner to modify your treatment plan as necessary.

Adhering to a dedicated polynucleotide aftercare plan contributes significantly to your skin's rejuvenation. Engaging in thoughtful post-treatment skincare, along with lifestyle changes and planned maintenance sessions, will ensure that you enjoy the long-term benefits of your polynucleotide injections.

How Much Do Polynucleotide Injections Cost?

The cost of polynucleotide injections can vary, but here's a general breakdown to help you plan:

  • Per session: Typically ranges from £200 to £600, depending on the clinic, practitioner expertise, and product used.
  • Treatment course: Most patients require 3 to 5 sessions spaced over several weeks for best results.
  • Packages: Some clinics offer discounts or bundled pricing for multiple sessions, so it’s worth asking about available deals.
  • Additional costs: Budget for aftercare products and follow-up appointments, which may not always be included in the session price.

Being aware of the full cost, including extras, can help you make informed decisions and avoid surprises during your treatment journey.

Latest Advances in Polynucleotide Injection Technology (2025)

As the field of aesthetic medicine continues to evolve, the advances in polynucleotide technology have gained significant attention. 

Recent innovations focus on enhancing the application techniques and formulation of these injections, ensuring improved efficacy and patient satisfaction. With each new development, practitioners are better equipped to provide treatments that result in rejuvenated skin and overall enhanced aesthetics.

Innovations and Future Trends

The future trends in polynucleotide injections indicate a shift towards tailor-made solutions for individual patient needs. Advancements in delivery systems, such as micro-needling combined with polynucleotide therapies, are emerging as popular choices, yielding remarkable results in skin texture and elasticity. 

Continuous research is driving the development of more effective formulations, paving the way for more personalised treatment plans.

Expert Opinions and Clinical Studies

Experts in the field have shared their insights on polynucleotide injections through various clinical studies, underscoring the potential benefits of polynucleotide treatments. These studies highlight not only the efficacy but also the safety profile of these injections, reinforcing their place in contemporary aesthetic practices. 

As new data emerges, it is clear that keeping abreast of these clinical findings will empower you to make informed choices regarding your skincare and treatment options.

Before You Go…

As polynucleotide injections continue to reshape the landscape of aesthetic treatments, staying informed is key to making confident, well-rounded decisions about your skincare. If you’re curious to dive deeper into this growing field, whether it's comparing injectable options, learning about the latest technologies, or finding expert advice, explore our related articles for more insights. Your journey to healthier, more radiant skin starts with knowledge.

Read More

  • Do polynucleotides make you look younger?
  • How quickly do polynucleotides work?
  • Can polynucleotides help acne?
  • Can I sleep after polynucleotides?

About Institute of Medical Physics

The Institute of Medical Physics, founded by Dr. Emanuel Paleco, is a premier medical laboratory specialising in Medical and Aesthetic Laser Science.

With a flagship clinic in King’s Cross and additional locations in North London and Essex, the Institute is at the forefront of laser science innovation. Experience advanced laser science and innovative medical treatments.

Book a consultation with Dr. Emanuel Paleco and his expert team at the Institute of Medical Physics.

FAQs

What are the primary benefits of polynucleotide injections?

The primary benefits include skin repair capabilities, anti-aging effects, and improvements in hydration and elasticity. These injections stimulate collagen production, enhance skin texture, and can help reduce fine lines and address issues like acne scarring.

How do polynucleotide injections differ from hyaluronic acid treatments?

While hyaluronic acid mainly adds volume to the skin, polynucleotide injections stimulate the body's natural regenerative processes, offering unique benefits such as promoting tissue repair and fighting free radicals, which can lead to a more youthful appearance.

What can I expect during the polynucleotide injection procedure?

During the procedure, a qualified practitioner will clean the treatment area and administer the injections using a fine needle. You can expect minimal discomfort, and the process usually takes around 30 minutes, depending on the areas treated, which may include the full face, under-eye regions, and jawline.

Are there any side effects associated with polynucleotide injections?

Yes, common side effects include redness, swelling, and tenderness at the injection sites, often considered an inflammatory response. Rare side effects may occur, and it is essential to discuss these with your practitioner before treatment.

Who should consider getting polynucleotide injections?

Ideal candidates are typically older adults experiencing moderate tissue laxity and seeking skin rejuvenation. However, individuals with specific health concerns or conditions should avoid these treatments, which a practitioner will discuss with you during the consultation.

Date First Published:
August 16, 2025
Our Research is Led by Dr. Emanuel Paleco World Renowned Biophysicist
Dr Emmanuel
1000+
Medical Doctors Trained
406+
Trademarks in his field
30+
Years of research
10+
Prestigious Research Awards

By -

Dr. Emanuel Paleco, PhD

August 16, 2025

Institute of Medical Physics