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Can Polynucleotides Treatments Help Acne Scars?

Can Polynucleotides Treatments Help Acne Scars?

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If you’re exploring advanced solutions for acne and its long-term effects, polynucleotide treatments are quickly emerging as a compelling option. Derived from naturally occurring DNA fragments, polynucleotides are gaining attention for their ability to support skin repair, reduce inflammation, and improve overall texture.

Since acne can leave behind stubborn scars and impact skin confidence, treatments that promote regeneration at the cellular level may offer real benefits. Here, we’ll examine how polynucleotides work and their potential role in supporting clearer, healthier skin.

Key Takeaways

  • Polynucleotides are derived from DNA and may aid in skin rejuvenation.
  • They can play a role in reducing the appearance of acne scars.
  • This treatment may enhance overall skin texture.
  • Exploring polynucleotide options could boost your confidence.
  • Understanding how these compounds function is essential for effective acne treatment.

What Are Polynucleotides and How Do They Work?

Polynucleotides are complex molecules composed of long chains of nucleotides. These nucleotides serve as the building blocks of DNA and RNA within cellular processes. When administered through injections or topical applications, polynucleotides can greatly influence skin health and repair.

Overview of Polynucleotide Composition

The structure of polynucleotides consists of sequences of nucleotides, which are organic molecules made up of a sugar, a phosphate group, and a nitrogenous base. This unique configuration allows polynucleotides to engage with skin cells, particularly fibroblasts. Fibroblasts are essential for collagen production, vital for maintaining skin elasticity and firmness.

Mechanism of Action in Skin Repair

When introduced into the skin, polynucleotides activate fibroblasts, promoting collagen production. This process is fundamental for skin repair, especially for addressing concerns such as acne scars.

The regenerative properties of polynucleotides facilitate the reduction of inflammation and support overall skin rejuvenation. Their ability to enhance skin texture and resilience makes them an invaluable asset in modern aesthetic treatments.

Understanding Acne and Its Causes

Acne is a complex skin condition that arises from various factors and affects a significant portion of the population, particularly during adolescence. By 2021, 14.6% of adolescents and young people were diagnosed with acne, highlighting its widespread impact.

This common skin concern can manifest in different forms, often leading to persistent inflammation and disruption of the skin's natural balance. Understanding the various types of acne and the challenges of treating acne-prone skin is essential to identifying the most effective treatment options available.

Common Types of Acne and Skin Inflammation

Several types of acne exist, each presenting unique characteristics:

  • Comedonal Acne: Characterised by blocked pores filled with oil and dead skin cells, often leading to blackheads and whiteheads.
  • Inflammatory Acne: Involves red and swollen spots, which can be painful and are often due to bacterial growth.
  • Nodular Acne: Deep, painful lumps beneath the skin that do not always come to a head, often resulting in severe skin inflammation.

Each type can contribute to the development of acne scars, making early intervention essential for effective acne treatment.

Challenges in Treating Acne-Prone Skin

Addressing acne-prone skin can be challenging for several reasons:

  • Many conventional treatments may not provide consistent results, leading to sustained skin concerns.
  • Acne scars and hyperpigmentation can persist long after the active acne has cleared, affecting the overall appearance of the skin.
  • The psychological impact of acne, including anxiety and low self-esteem, often complicates the healing process.

Pursuing innovative treatments, such as polynucleotide applications, may help tackle both the immediate effects of skin inflammation and the long-term issues associated with acne scars.

How Polynucleotides May Benefit Acne Treatment

Polynucleotide injections offer numerous advantages for acne treatment. By promoting tissue regeneration and reducing inflammation, they support the healing of active breakouts while improving overall skin texture and resilience and youthfulness. 

Anti-Inflammatory and Healing Properties

The benefits of polynucleotide treatment prominently include their anti-inflammatory nature. By significantly reducing swelling and redness, they alleviate the discomfort often associated with acne flare-ups. In addition, the healing properties of polynucleotides aid in repairing existing skin damage, leading to a more balanced complexion.

Stimulating Skin Regeneration and Reducing Scarring

Polynucleotides play an important role in stimulating skin regeneration. This process fosters the production of new collagen, which is vital for maintaining skin elasticity and firmness. This process not only improves skin structure but also contributes to a naturally more youthful appearance, a benefit that’s increasingly recognised in clinical use and aesthetic practice. 

Over time, this mechanism can effectively reduce acne scars, helping you achieve a smoother skin texture. Enhanced hydration from polynucleotides further contributes to improved overall skin health, making them a valuable addition to any acne treatment regimen.

Polynucleotides in Combination with Other Acne Treatments

Polynucleotide therapy is increasingly being explored as a complementary option alongside conventional acne treatments. Rather than replacing established therapies, it supports the skin’s repair processes, helping reduce post-inflammatory redness, promote balanced hydration, and accelerate recovery,  particularly in irritated or treatment-sensitive skin.

Complementing Topical and Oral Medications

While polynucleotides can be used alongside other acne treatments, it's essential to approach this combination cautiously. Integrating polynucleotides with topical medications and oral acne treatments may (theoretically) enhance the healing process. 

However, the specific interactions and optimal protocols require careful consideration to avoid potential adverse effects. It’s best to consult with your healthcare provider before mixing them together. 

Enhancing Results with Professional Skin Therapies

Combining polynucleotides with in-clinic treatments such as micro-needling or chemical peels may deliver improved results in some cases, although discretion and advice from medical professionals is advised. These procedures can create controlled micro-injuries or exfoliation pathways in the skin, which may support better absorption of topically applied polynucleotides.

This combined approach is thought to enhance overall skin regeneration and may contribute to improved texture and reduced appearance of post-acne marks, though outcomes can vary depending on individual skin conditions and treatment settings.

Treatment Process: What to Expect with Polynucleotides for Acne

The treatment process for addressing acne using polynucleotide injections involves specific steps designed to enhance skin recovery and reduce inflammation. Understanding these elements can help you prepare for the procedure and set realistic expectations.

Procedure Details and Frequency

During your treatment, a qualified practitioner will administer polynucleotide injections directly into the affected areas of your skin. Each session is generally completed within approximately 30 minutes, allowing for a quick visit.

Depending on your individual skin condition, you may undergo these treatments every two to four weeks. This schedule is tailored to aid the benefits of the injections while ensuring your skin has adequate time to heal and respond.

Recovery Time and Side Effects

After the injections, you may notice some temporary side effects. Commonly reported effects include slight redness and mild swelling at the injection sites. These side effects are usually transient and typically resolve within a few hours.

Most patients can return to their daily activities almost immediately, experiencing minimal interruption to their routine. Understanding the expected recovery time and potential side effects can alleviate concerns and provide peace of mind during the treatment process.

Who Should Consider Polynucleotide Treatments for Acne?

Polynucleotide treatments are ideal for those looking to boost skin regeneration and improve texture. However, they are not suitable for everyone. Individuals with certain health conditions or allergies should avoid this treatment. 

Suitability for Different Skin Types

Polynucleotide treatments can be tailored to suit a variety of skin types, making them a versatile option in aesthetic care:

  • Oily and Acne-Prone Skin: Polynucleotides help reduce inflammation and support healing, making them particularly beneficial for those dealing with active acne or post-acne scarring.
  • Dry and Dehydrated Skin: The hydrating properties of polynucleotides promote moisture retention and skin barrier repair, improving texture and reducing flakiness.
  • Sensitive Skin: Due to their soothing and anti-inflammatory effects, polynucleotide injections are often well-tolerated by sensitive skin types, helping to calm redness and irritation without harsh side effects.
  • Aging or Mature Skin: By stimulating collagen and elastin production, polynucleotides enhance skin firmness and elasticity, addressing common concerns such as fine lines and loss of volume.

To achieve optimal results, treatment protocols should be personalized according to your skin type and concerns. Regular consultations with your dermatologist are essential to adjust the approach and ensure your skin responds well to the therapy.

Precautions and When to Consult a Dermatologist

Before undergoing polynucleotide treatments, it’s important to take several precautions to ensure safety and effectiveness:

  • Consult a Qualified Dermatologist such as the Institute of Medical Physics: A professional evaluation of your skin condition and medical history is crucial to identify any contraindications and to develop a personalised treatment plan.
  • Avoid Active Infections or Skin Conditions: Treatment should be postponed if you have active skin infections, open wounds, or inflammatory skin diseases in the treatment area.
  • Inform About Allergies and Medications: Disclose any known allergies, especially to components of the treatment, and any medications you are currently taking, as these can affect treatment suitability.
  • Pregnancy and Breastfeeding: Polynucleotide treatments are generally not recommended during pregnancy or breastfeeding due to limited safety data.
  • Skin Sensitivity and Recent Procedures: If you have highly sensitive skin or have recently undergone other aesthetic procedures (like chemical peels or laser treatments), discuss appropriate timing and precautions with your dermatologist.
  • Monitor for Adverse Reactions: After treatment, watch for unusual or prolonged redness, swelling, or discomfort, and contact your provider promptly if these occur.

Taking these precautions and maintaining open communication with your dermatologist will help optimise your treatment outcomes and minimise risks

Are There Clinical Studies Supporting Polynucleotides for Acne?

Current clinical studies indicate that polynucleotides show significant potential in aesthetic medicine, particularly in the realm of acne treatment. Research on acne treatment suggests that polynucleotide injections can enhance skin elasticity and markedly reduce the appearance of scars, providing you with a dual benefit that addresses both active breakouts and their aftermath.

While the efficacy of polynucleotides is supported by promising findings, it is important to note that further investigation is essential. Continued research on acne treatment will help clarify the underlying mechanisms of how polynucleotides function, ultimately leading to the establishment of standardised treatment protocols. This ongoing exploration is crucial to ensure that you receive the most effective care possible.

Before You Go...

Polynucleotide therapy is gaining recognition as a promising complement to traditional acne treatments, offering regenerative support for both active breakouts and lingering scars. As our understanding of skin science continues to evolve, staying informed about innovative therapies can empower you to make more confident skincare decisions. 

If you’re interested in learning more about how polynucleotides compare with other injectables or their broader role in skin health, explore our related articles for deeper insight and expert guidance.

Read More

  • Can I sleep after polynucleotides?
  • Are polynucleotides painful?
  • What are polynucleotides for eyes?

About Institute of Medical Physics

The Institute of Medical Physics, founded by Dr. Emanuel Paleco, is a premier medical laboratory specialising in Medical and Aesthetic Laser Science.

With a flagship clinic in King’s Cross and additional locations in North London and Essex, the Institute is at the forefront of laser science innovation. Experience advanced laser science and innovative medical treatments.

Book a consultation with Dr. Emanuel Paleco and his expert team at the Institute of Medical Physics.

FAQs

What are polynucleotides?

Polynucleotides are naturally occurring substances derived from DNA, composed of nucleotide chains that serve as the building blocks of DNA and RNA.

How do polynucleotides work in treating acne?

When injected into the skin, polynucleotides stimulate fibroblasts to produce collagen and elastin, aiding in skin repair, reducing inflammation, and improving skin elasticity and texture.

Are there specific benefits of polynucleotides for acne scarring?

Yes, polynucleotides can help reduce the appearance of acne scars by promoting collagen production, accelerating skin regeneration, and improving skin hydration.

Can polynucleotide treatments be combined with other acne therapies?

While polynucleotides may complement topical and oral acne medications, it’s best to consult with your specialist before taking this path of treatment.

What can I expect during a polynucleotide treatment session?

Each session typically lasts around 30 minutes, with injectable treatments administered every two to four weeks, depending on individual skin conditions.

Date First Published:
August 14, 2025
Our Research is Led by Dr. Emanuel Paleco World Renowned Biophysicist
Dr Emmanuel
1000+
Medical Doctors Trained
406+
Trademarks in his field
30+
Years of research
10+
Prestigious Research Awards

Can Polynucleotides Treatments Help Acne Scars?

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If you’re exploring advanced solutions for acne and its long-term effects, polynucleotide treatments are quickly emerging as a compelling option. Derived from naturally occurring DNA fragments, polynucleotides are gaining attention for their ability to support skin repair, reduce inflammation, and improve overall texture.

Since acne can leave behind stubborn scars and impact skin confidence, treatments that promote regeneration at the cellular level may offer real benefits. Here, we’ll examine how polynucleotides work and their potential role in supporting clearer, healthier skin.

Key Takeaways

  • Polynucleotides are derived from DNA and may aid in skin rejuvenation.
  • They can play a role in reducing the appearance of acne scars.
  • This treatment may enhance overall skin texture.
  • Exploring polynucleotide options could boost your confidence.
  • Understanding how these compounds function is essential for effective acne treatment.

What Are Polynucleotides and How Do They Work?

Polynucleotides are complex molecules composed of long chains of nucleotides. These nucleotides serve as the building blocks of DNA and RNA within cellular processes. When administered through injections or topical applications, polynucleotides can greatly influence skin health and repair.

Overview of Polynucleotide Composition

The structure of polynucleotides consists of sequences of nucleotides, which are organic molecules made up of a sugar, a phosphate group, and a nitrogenous base. This unique configuration allows polynucleotides to engage with skin cells, particularly fibroblasts. Fibroblasts are essential for collagen production, vital for maintaining skin elasticity and firmness.

Mechanism of Action in Skin Repair

When introduced into the skin, polynucleotides activate fibroblasts, promoting collagen production. This process is fundamental for skin repair, especially for addressing concerns such as acne scars.

The regenerative properties of polynucleotides facilitate the reduction of inflammation and support overall skin rejuvenation. Their ability to enhance skin texture and resilience makes them an invaluable asset in modern aesthetic treatments.

Understanding Acne and Its Causes

Acne is a complex skin condition that arises from various factors and affects a significant portion of the population, particularly during adolescence. By 2021, 14.6% of adolescents and young people were diagnosed with acne, highlighting its widespread impact.

This common skin concern can manifest in different forms, often leading to persistent inflammation and disruption of the skin's natural balance. Understanding the various types of acne and the challenges of treating acne-prone skin is essential to identifying the most effective treatment options available.

Common Types of Acne and Skin Inflammation

Several types of acne exist, each presenting unique characteristics:

  • Comedonal Acne: Characterised by blocked pores filled with oil and dead skin cells, often leading to blackheads and whiteheads.
  • Inflammatory Acne: Involves red and swollen spots, which can be painful and are often due to bacterial growth.
  • Nodular Acne: Deep, painful lumps beneath the skin that do not always come to a head, often resulting in severe skin inflammation.

Each type can contribute to the development of acne scars, making early intervention essential for effective acne treatment.

Challenges in Treating Acne-Prone Skin

Addressing acne-prone skin can be challenging for several reasons:

  • Many conventional treatments may not provide consistent results, leading to sustained skin concerns.
  • Acne scars and hyperpigmentation can persist long after the active acne has cleared, affecting the overall appearance of the skin.
  • The psychological impact of acne, including anxiety and low self-esteem, often complicates the healing process.

Pursuing innovative treatments, such as polynucleotide applications, may help tackle both the immediate effects of skin inflammation and the long-term issues associated with acne scars.

How Polynucleotides May Benefit Acne Treatment

Polynucleotide injections offer numerous advantages for acne treatment. By promoting tissue regeneration and reducing inflammation, they support the healing of active breakouts while improving overall skin texture and resilience and youthfulness. 

Anti-Inflammatory and Healing Properties

The benefits of polynucleotide treatment prominently include their anti-inflammatory nature. By significantly reducing swelling and redness, they alleviate the discomfort often associated with acne flare-ups. In addition, the healing properties of polynucleotides aid in repairing existing skin damage, leading to a more balanced complexion.

Stimulating Skin Regeneration and Reducing Scarring

Polynucleotides play an important role in stimulating skin regeneration. This process fosters the production of new collagen, which is vital for maintaining skin elasticity and firmness. This process not only improves skin structure but also contributes to a naturally more youthful appearance, a benefit that’s increasingly recognised in clinical use and aesthetic practice. 

Over time, this mechanism can effectively reduce acne scars, helping you achieve a smoother skin texture. Enhanced hydration from polynucleotides further contributes to improved overall skin health, making them a valuable addition to any acne treatment regimen.

Polynucleotides in Combination with Other Acne Treatments

Polynucleotide therapy is increasingly being explored as a complementary option alongside conventional acne treatments. Rather than replacing established therapies, it supports the skin’s repair processes, helping reduce post-inflammatory redness, promote balanced hydration, and accelerate recovery,  particularly in irritated or treatment-sensitive skin.

Complementing Topical and Oral Medications

While polynucleotides can be used alongside other acne treatments, it's essential to approach this combination cautiously. Integrating polynucleotides with topical medications and oral acne treatments may (theoretically) enhance the healing process. 

However, the specific interactions and optimal protocols require careful consideration to avoid potential adverse effects. It’s best to consult with your healthcare provider before mixing them together. 

Enhancing Results with Professional Skin Therapies

Combining polynucleotides with in-clinic treatments such as micro-needling or chemical peels may deliver improved results in some cases, although discretion and advice from medical professionals is advised. These procedures can create controlled micro-injuries or exfoliation pathways in the skin, which may support better absorption of topically applied polynucleotides.

This combined approach is thought to enhance overall skin regeneration and may contribute to improved texture and reduced appearance of post-acne marks, though outcomes can vary depending on individual skin conditions and treatment settings.

Treatment Process: What to Expect with Polynucleotides for Acne

The treatment process for addressing acne using polynucleotide injections involves specific steps designed to enhance skin recovery and reduce inflammation. Understanding these elements can help you prepare for the procedure and set realistic expectations.

Procedure Details and Frequency

During your treatment, a qualified practitioner will administer polynucleotide injections directly into the affected areas of your skin. Each session is generally completed within approximately 30 minutes, allowing for a quick visit.

Depending on your individual skin condition, you may undergo these treatments every two to four weeks. This schedule is tailored to aid the benefits of the injections while ensuring your skin has adequate time to heal and respond.

Recovery Time and Side Effects

After the injections, you may notice some temporary side effects. Commonly reported effects include slight redness and mild swelling at the injection sites. These side effects are usually transient and typically resolve within a few hours.

Most patients can return to their daily activities almost immediately, experiencing minimal interruption to their routine. Understanding the expected recovery time and potential side effects can alleviate concerns and provide peace of mind during the treatment process.

Who Should Consider Polynucleotide Treatments for Acne?

Polynucleotide treatments are ideal for those looking to boost skin regeneration and improve texture. However, they are not suitable for everyone. Individuals with certain health conditions or allergies should avoid this treatment. 

Suitability for Different Skin Types

Polynucleotide treatments can be tailored to suit a variety of skin types, making them a versatile option in aesthetic care:

  • Oily and Acne-Prone Skin: Polynucleotides help reduce inflammation and support healing, making them particularly beneficial for those dealing with active acne or post-acne scarring.
  • Dry and Dehydrated Skin: The hydrating properties of polynucleotides promote moisture retention and skin barrier repair, improving texture and reducing flakiness.
  • Sensitive Skin: Due to their soothing and anti-inflammatory effects, polynucleotide injections are often well-tolerated by sensitive skin types, helping to calm redness and irritation without harsh side effects.
  • Aging or Mature Skin: By stimulating collagen and elastin production, polynucleotides enhance skin firmness and elasticity, addressing common concerns such as fine lines and loss of volume.

To achieve optimal results, treatment protocols should be personalized according to your skin type and concerns. Regular consultations with your dermatologist are essential to adjust the approach and ensure your skin responds well to the therapy.

Precautions and When to Consult a Dermatologist

Before undergoing polynucleotide treatments, it’s important to take several precautions to ensure safety and effectiveness:

  • Consult a Qualified Dermatologist such as the Institute of Medical Physics: A professional evaluation of your skin condition and medical history is crucial to identify any contraindications and to develop a personalised treatment plan.
  • Avoid Active Infections or Skin Conditions: Treatment should be postponed if you have active skin infections, open wounds, or inflammatory skin diseases in the treatment area.
  • Inform About Allergies and Medications: Disclose any known allergies, especially to components of the treatment, and any medications you are currently taking, as these can affect treatment suitability.
  • Pregnancy and Breastfeeding: Polynucleotide treatments are generally not recommended during pregnancy or breastfeeding due to limited safety data.
  • Skin Sensitivity and Recent Procedures: If you have highly sensitive skin or have recently undergone other aesthetic procedures (like chemical peels or laser treatments), discuss appropriate timing and precautions with your dermatologist.
  • Monitor for Adverse Reactions: After treatment, watch for unusual or prolonged redness, swelling, or discomfort, and contact your provider promptly if these occur.

Taking these precautions and maintaining open communication with your dermatologist will help optimise your treatment outcomes and minimise risks

Are There Clinical Studies Supporting Polynucleotides for Acne?

Current clinical studies indicate that polynucleotides show significant potential in aesthetic medicine, particularly in the realm of acne treatment. Research on acne treatment suggests that polynucleotide injections can enhance skin elasticity and markedly reduce the appearance of scars, providing you with a dual benefit that addresses both active breakouts and their aftermath.

While the efficacy of polynucleotides is supported by promising findings, it is important to note that further investigation is essential. Continued research on acne treatment will help clarify the underlying mechanisms of how polynucleotides function, ultimately leading to the establishment of standardised treatment protocols. This ongoing exploration is crucial to ensure that you receive the most effective care possible.

Before You Go...

Polynucleotide therapy is gaining recognition as a promising complement to traditional acne treatments, offering regenerative support for both active breakouts and lingering scars. As our understanding of skin science continues to evolve, staying informed about innovative therapies can empower you to make more confident skincare decisions. 

If you’re interested in learning more about how polynucleotides compare with other injectables or their broader role in skin health, explore our related articles for deeper insight and expert guidance.

Read More

  • Can I sleep after polynucleotides?
  • Are polynucleotides painful?
  • What are polynucleotides for eyes?

About Institute of Medical Physics

The Institute of Medical Physics, founded by Dr. Emanuel Paleco, is a premier medical laboratory specialising in Medical and Aesthetic Laser Science.

With a flagship clinic in King’s Cross and additional locations in North London and Essex, the Institute is at the forefront of laser science innovation. Experience advanced laser science and innovative medical treatments.

Book a consultation with Dr. Emanuel Paleco and his expert team at the Institute of Medical Physics.

FAQs

What are polynucleotides?

Polynucleotides are naturally occurring substances derived from DNA, composed of nucleotide chains that serve as the building blocks of DNA and RNA.

How do polynucleotides work in treating acne?

When injected into the skin, polynucleotides stimulate fibroblasts to produce collagen and elastin, aiding in skin repair, reducing inflammation, and improving skin elasticity and texture.

Are there specific benefits of polynucleotides for acne scarring?

Yes, polynucleotides can help reduce the appearance of acne scars by promoting collagen production, accelerating skin regeneration, and improving skin hydration.

Can polynucleotide treatments be combined with other acne therapies?

While polynucleotides may complement topical and oral acne medications, it’s best to consult with your specialist before taking this path of treatment.

What can I expect during a polynucleotide treatment session?

Each session typically lasts around 30 minutes, with injectable treatments administered every two to four weeks, depending on individual skin conditions.

Date First Published:
August 14, 2025
Our Research is Led by Dr. Emanuel Paleco World Renowned Biophysicist
Dr Emmanuel
1000+
Medical Doctors Trained
406+
Trademarks in his field
30+
Years of research
10+
Prestigious Research Awards

By -

Dr. Emanuel Paleco, PhD

August 14, 2025

Institute of Medical Physics